Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655975 | 0.89 | PPARG (0.44) | PPARAPPARGSIGMAR1KMT2APOLB | |
| SCHEMBL13655821 | 0.87 | MTNR1A (0.38) | PPARAPPARGSIGMAR1GRIN1KCNH2 | |
| SCHEMBL4073429 | 0.84 | PPARA (0.60) | PPARAPPARG | |
| SCHEMBL4076444 | 0.83 | PPARA (0.49) | PPARAPPARGKMT2AFAAH | |
| SCHEMBL13655922 | 0.83 | PPARA (0.47) | PPARAPPARGKCNH2 | |
| SCHEMBL13655828 | 0.83 | PPARA (0.47) | PPARAPPARGKCNH2 | |
| SCHEMBL14305541 | 0.79 | PPARA (0.38) | PPARAPPARGSIGMAR1GRIN1KCNH2 | |
| SCHEMBL14305138 | 0.78 | MTNR1A (0.40) | FAAHSLC2A1 | |
| SCHEMBL13655792 | 0.77 | PPARA (0.50) | PPARAPPARGSIGMAR1GRIN1KCNH2 | |
| SCHEMBL13655823 | 0.77 | PPARA (0.50) | PPARAPPARGSIGMAR1GRIN1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598293-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7314889-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2008-01-01 | — | — | US | disclosed |