Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GMNN | O75496 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875233 | 0.89 | ALDH1A1 (0.64) | GABRA1GABRB2HTTMAPTMEN1 | |
| SCHEMBL2843776 | 0.89 | ALDH1A1 (0.64) | GABRA1GABRB2HTTMAPTMEN1 | |
| SCHEMBL29875304 | 0.87 | KDM4E (0.54) | GABRA1GABRB2MAPTMEN1KMT2A | |
| SCHEMBL27952677 | 0.87 | KDM4E (0.54) | GABRA1GABRB2MAPTMEN1KMT2A | |
| SCHEMBL30125359 | 0.85 | GABRA1 (0.54) | GABRA1GABRB2HTTMAPTMEN1 | |
| SCHEMBL83892 | 0.85 | GABRA1 (0.54) | GABRA1GABRB2HTTMAPTMEN1 | |
| SCHEMBL10603909 | 0.84 | HSD17B3 (0.53) | GABRA1GABRB2HTTMAPTMEN1 | |
| SCHEMBL9857065 | 0.84 | MEN1 (0.62) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15732279 | 0.83 | MEN1 (0.60) | HTTMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15659633 | 0.83 | MEN1 (0.60) | HTTMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605182-B2 | drug conjugate with a marker for imaging to detect by fluorescence, X-ray, computerized tomography, magnetic resonance imaging (MRI), radio-isotope scan, single photon emission tomography (SPECT) or positron emission tomography (PET scan); targeting anticancer drugs to the tumor in body | APOSENSE LTD. (IL) | 2009-10-20 | — | — | US | disclosed |
| US-7605182-B2 | drug conjugate with a marker for imaging to detect by fluorescence, X-ray, computerized tomography, magnetic resonance imaging (MRI), radio-isotope scan, single photon emission tomography (SPECT) or positron emission tomography (PET scan); targeting anticancer drugs to the tumor in body | APOSENSE LTD. (IL) | 2009-10-20 | — | — | US | disclosed |
| US-20070031326-A1 | Compounds that selectively bind to membranes of apoptotic cells | NEUROSURVIVAL TECHNOLOGIES, LTD. (IL) | 2007-02-08 | — | — | US | disclosed |
| US-20070031326-A1 | Compounds that selectively bind to membranes of apoptotic cells | NEUROSURVIVAL TECHNOLOGIES, LTD. (IL) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070031326-A1 | Compounds that selectively bind to membranes of apoptotic cells | BAD, BID, MCL1 | GABRA1 3955/4885GABRB2 3333/4885HTT 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.