SCHEMBL2843776

SCHEMBL2843776

CCCCC(=O)c1cccc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
MAPT P10636 3/20 0.64
HPGD P15428 3/20 0.64
KDM4E B2RXH2 2/20 0.64
MEN1 O00255 2/20 0.64
GMNN O75496 2/20 0.64
LMNA P02545 2/20 0.64
POLB P06746 2/20 0.64
MAPK1 P28482 2/20 0.64
BLM P54132 2/20 0.64
PMP22 Q01453 2/20 0.64
KMT2A Q03164 2/20 0.64
NPSR1 Q6W5P4 2/20 0.64
CMKLR1 Q99788 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
CYP2C9 P11712 2/20 0.64
TP53 P04637 1/20 0.64
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64
CYP2D6 P10635 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29875233 1.00 ALDH1A1 (0.64) ALDH1A1MAPTHPGDKDM4EMEN1
SCHEMBL9857065 0.95 MEN1 (0.62) ALDH1A1MAPTHPGDKDM4EMEN1
SCHEMBL7913756 0.93 MEN1 (0.60) ALDH1A1MAPTHPGDKDM4EMEN1
SCHEMBL15655785 0.93 MEN1 (0.60) ALDH1A1MAPTHPGDKDM4EMEN1
SCHEMBL15658636 0.93 MEN1 (0.60) ALDH1A1MAPTHPGDKDM4EMEN1
SCHEMBL15659633 0.93 MEN1 (0.60) ALDH1A1MAPTHPGDKDM4EMEN1
SCHEMBL15732279 0.93 MEN1 (0.60) ALDH1A1MAPTHPGDKDM4EMEN1
SCHEMBL11352446 0.93 MEN1 (0.60) ALDH1A1MAPTHPGDKDM4EMEN1
SCHEMBL10798233 0.92 MEN1 (0.59) ALDH1A1MAPTHPGDKDM4EMEN1
SCHEMBL28376839 0.92 MEN1 (0.59) ALDH1A1MAPTHPGDKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8378216-B2 Energy cable PRYSMIAN S.P.A. (IT) 2013-02-19 US claimed
CN-101548340-B Energy cable PRYSMIAN CO LTD 2013-01-30 CN claimed
US-20100126756-A1 ENERGY CABLE PRYSMIAN CAVIESISTEMI ENERGIA (IT) 2010-05-27 US claimed
CN-101548340-A Energy cable PRYSMIAN CO LTD 2009-09-30 CN claimed
EP-2092535-A1 ENERGY CABLE Prysmian S.p.A. (IT) 2009-08-26 EP claimed
WO-2008058572-A1 ENERGY CABLE PRYSMIAN S.P.A. (IT) 2008-05-22 WO claimed
CN-114956933-A Marker containing isotope oxygen atom and preparation method and application thereof 清华大学 2022-08-30 CN disclosed
CN-105754099-B Composition and polymer 旭化成株式会社 2018-09-18 CN disclosed
EP-2092535-B1 ENERGY CABLE PRYSMIAN SPA (IT) 2017-01-18 EP disclosed
CN-103502315-A Composition and polymer ASAHI KASEI CHEMICALS CORP 2014-01-08 CN disclosed
US-8378216-B2 Energy cable PRYSMIAN S.P.A. (IT) 2013-02-19 US disclosed
CN-101548340-B Energy cable PRYSMIAN CO LTD 2013-01-30 CN disclosed
US-20100126756-A1 ENERGY CABLE PRYSMIAN CAVIESISTEMI ENERGIA (IT) 2010-05-27 US disclosed
US-20090221645-A1 Dihydroimidazothiazole Derivatives PROSIDION LIMITED (GB) 2009-09-03 US disclosed
US-20090221645-A1 Dihydroimidazothiazole Derivatives PROSIDION LIMITED (GB) 2009-09-03 US disclosed
US-20090221645-A1 Dihydroimidazothiazole Derivatives PROSIDION LIMITED (GB) 2009-09-03 US disclosed
EP-2092535-A1 ENERGY CABLE Prysmian S.p.A. (IT) 2009-08-26 EP disclosed
WO-2008058572-A1 ENERGY CABLE PRYSMIAN S.P.A. (IT) 2008-05-22 WO disclosed
CN-1027064-C Naphthalene derivatives EISAI CO LTD (JP) 1994-12-21 CN disclosed
CN-1043696-A NAPHTHALENE DERIVATIVES EISAI CO LTD (JP) 1990-07-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221645-A1 Dihydroimidazothiazole Derivatives TPH1, HTR3B, HTR1A ALDH1A1 195/4885MAPT 891/4885HPGD 935/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.