Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 6/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 3/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031516 | 0.80 | CASP3 (0.54) | CASP3SMN1; SMN2SENP7SENP6PIM1 | |
| SCHEMBL2704120 | 0.77 | C1R (0.68) | CASP3SMN1; SMN2SENP7SENP6KMT2A | |
| SCHEMBL13657347 | 0.77 | PIM1 (0.74) | PIM1CSNK2BPIM3PIM2CSNK2A2 | |
| SCHEMBL24546320 | 0.77 | SMN1; SMN2 (0.60) | CASP3SMN1; SMN2SENP7SENP6ADORA3 | |
| SCHEMBL25551888 | 0.76 | SMN1; SMN2 (0.63) | CASP3SMN1; SMN2SENP7SENP6ADORA3 | |
| SCHEMBL15766390 | 0.76 | KMT2A (0.51) | CASP3SMN1; SMN2SENP7SENP6PIM1 | |
| SCHEMBL23002155 | 0.76 | KMT2A (0.51) | CASP3SMN1; SMN2SENP7SENP6PIM1 | |
| SCHEMBL25898358 | 0.74 | SMN1; SMN2 (0.60) | CASP3SMN1; SMN2SENP7SENP6ADORA3 | |
| SCHEMBL15766125 | 0.74 | KMT2A (0.49) | CASP3SMN1; SMN2SENP7SENP6PIM1 | |
| SCHEMBL25729949 | 0.73 | SMN1; SMN2 (0.58) | CASP3SMN1; SMN2SENP7SENP6ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872052-B2 | Use of heterocyclic compounds as SCCE inhibitors | AREXIS AB (SE) | 2011-01-18 | — | — | US | disclosed |
| US-20060258651-A1 | Use of heterocyclic compounds as scce inhibitors | QUANTUM LTO HOLDINGS, LLC | 2006-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060258651-A1 | Use of heterocyclic compounds as scce inhibitors | RCE1, CTSE, SPINT2 | CASP3 1760/4885SMN1; SMN2 3806/4885SENP7 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.