Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.32 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.32 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13645453 | 0.84 | SENP1 (0.37) | MAPT | |
| SCHEMBL13645441 | 0.81 | SENP1 (0.41) | MAPT | |
| Ufiprazole SCHEMBL13645428 | 0.69 | BRS3 (0.42) | — | |
| Tenatoprazole SCHEMBL13657643 | 0.69 | DDAH1 (0.36) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657629 | 0.65 | DDAH1 (0.39) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657683 | 0.64 | DDAH1 (0.32) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657679 | 0.64 | DDAH1 (0.35) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657637 | 0.64 | DDAH1 (0.42) | DDAH1SARM1IDO2ENGASE | |
| Tenatoprazole SCHEMBL13657650 | 0.64 | DDAH1 (0.40) | DDAH1SARM1IDO2ENGASE | |
| SCHEMBL13657695 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258897-A1 | Substituted benzimidazoles | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258897-A1 | Substituted benzimidazoles | ABCB11, CYP2C19, HRH2 | ENPP3 1968/4885ENPP1 1397/4885ENPP2 3896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.