Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532646 | 0.75 | ESR1 (0.55) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL11152421 | 0.74 | ESR1 (0.65) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL1305524 | 0.74 | ALDH1A1 (0.77) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL20300595 | 0.72 | DRD2 (0.41) | SLC6A4SLC6A2 | |
| SCHEMBL121680 | 0.71 | KCNH2 (0.35) | — | |
| SCHEMBL8641485 | 0.71 | ESR1 (0.50) | ESR1ESR2ALDH1A1L3MBTL1ADORA3 | |
| SCHEMBL11890474 | 0.71 | ALDH1A1 (0.71) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL18059549 | 0.71 | ESR1 (0.71) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL23198924 | 0.70 | ALDH1A1 (1.00) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 | |
| SCHEMBL900958 | 0.70 | ESR1 (0.60) | ESR1ESR2ALDH1A1L3MBTL1PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343697-B2 | Electrophotographic photoconductor and image forming apparatus provided with the same | SHARP KABUSHIKI KAISHA (JP) | 2013-01-01 | — | — | US | disclosed |
| US-8343697-B2 | Electrophotographic photoconductor and image forming apparatus provided with the same | SHARP KABUSHIKI KAISHA (JP) | 2013-01-01 | — | — | US | disclosed |
| US-20090257777-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2009-10-15 | — | — | US | disclosed |
| US-20090257777-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2009-10-15 | — | — | US | disclosed |