SCHEMBL13658163

SCHEMBL13658163

COc1ccc(CN(Cc2ccc(OC)cc2)Cc2ccc(-c3ccc(CN(Cc4ccc(OC)cc4)Cc4ccc(OC)cc4)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.57
HRH3 Q9Y5N1 3/20 0.56
APLNR P35414 2/20 0.53
IDO1 P14902 2/20 0.50
ESR2 Q92731 1/20 0.50
PYCR1 P32322 1/20 0.50
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CYP19A1 P11511 1/20 0.48
ALDH1A1 P00352 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
AGXT P21549 1/20 0.47
LTA4H P09960 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
AOC3 Q16853 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12049800 0.93 APLNR (0.59) APLNRIDO1PYCR1CA12CA1
SCHEMBL5270803 0.93 APLNR (0.59) APLNRIDO1PYCR1CA12CA1
SCHEMBL19700309 0.89 KDM4E (0.54) MAOBHRH3APLNRCYP19A1SMN1; SMN2
SCHEMBL16701049 0.85 LTA4H (0.67) APLNRHTTLTA4H
SCHEMBL18268268 0.83 APLNR (0.50) APLNRIDO1PYCR1CA12CA1
SCHEMBL10076308 0.83 HRH3 (0.61) HRH3APLNRIDO1AOC3
SCHEMBL19708786 0.82 CYP17A1 (0.50) CYP19A1
SCHEMBL3236630 0.80 MAOB (0.59) MAOBIDO1ESR2CA12CA1
SCHEMBL6059611 0.79 LTA4H (0.71) MAOBIDO1ESR2CA12CA1
SCHEMBL22451382 0.79 LTA4H (0.71) MAOBIDO1ESR2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8343697-B2 Electrophotographic photoconductor and image forming apparatus provided with the same SHARP KABUSHIKI KAISHA (JP) 2013-01-01 US disclosed
US-8343697-B2 Electrophotographic photoconductor and image forming apparatus provided with the same SHARP KABUSHIKI KAISHA (JP) 2013-01-01 US disclosed
US-20090257777-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME SHARP KABUSHIKI KAISHA (JP) 2009-10-15 US disclosed
US-20090257777-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME SHARP KABUSHIKI KAISHA (JP) 2009-10-15 US disclosed