Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | APLNR | P35414 | 1/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL23429845 | 0.89 | HRH3 (0.56) | HRH3TSHRMAPK1APLNR | |
| SCHEMBL12049800 | 0.89 | APLNR (0.59) | TSHRMAPK1APLNRAOC3IDO1 | |
| SCHEMBL5270803 | 0.89 | APLNR (0.59) | TSHRMAPK1APLNRAOC3IDO1 | |
| SCHEMBL22340700 | 0.88 | TSHR (0.75) | TSHRMAPK1 | |
| SCHEMBL22340500 | 0.88 | HRH3 (0.55) | HRH3TSHRMAPK1AOC3 | |
| SCHEMBL14382168 | 0.88 | TSHR (0.51) | HRH3TSHRMAPK1APLNRAOC3 | |
| SCHEMBL20871857 | 0.85 | MAPT (0.54) | TSHRMAPK1 | |
| SCHEMBL17230510 | 0.85 | TSHR (0.49) | TSHRMAPK1AOC3 | |
| SCHEMBL11453792 | 0.85 | TAAR1 (0.52) | HRH3TSHRMAPK1APLNRAOC3 | |
| SCHEMBL20871868 | 0.84 | TSHR (0.53) | HRH3TSHRMAPK1APLNRAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11636986-B2 | Flexible, biodegradable and biocompatible supercondenser | BIO-ON S.P.A. (IT) | 2023-04-25 | — | — | US | claimed |
| US-20220028628-A1 | FLEXIBLE, BIODEGRADABLE AND BIOCOMPATIBLE SUPERCONDENSER | BIO ON S.P.A. (IT) | 2022-01-27 | — | — | US | claimed |
| EP-3707132-B1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | UNIV PARIS SACLAY (FR) | 2024-07-17 | — | — | EP | disclosed |
| US-11680250-B2 | Light-driven system and methods for chemical modification of an organic substrate | UNIVERSITY OF COPENHAGEN (DK) | 2023-06-20 | — | — | US | disclosed |
| US-11636986-B2 | Flexible, biodegradable and biocompatible supercondenser | BIO-ON S.P.A. (IT) | 2023-04-25 | — | — | US | disclosed |
| EP-3227292-B1 | 4H-PYRIDO[1,2-a]PYRIMIDIN-4-ONE COMPOUNDS | ALTERITY THERAPEUTICS LTD (AU) | 2022-03-09 | — | — | EP | disclosed |
| US-20220028628-A1 | FLEXIBLE, BIODEGRADABLE AND BIOCOMPATIBLE SUPERCONDENSER | BIO ON S.P.A. (IT) | 2022-01-27 | — | — | US | disclosed |
| EP-3322802-B1 | LIGHT-DRIVEN SYSTEM AND METHODS FOR CHEMICAL MODIFICATION OF AN ORGANIC SUBSTRATE | UNIV COPENHAGEN (DK) | 2022-01-19 | — | — | EP | disclosed |
| EP-3929198-A1 | HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2021-12-29 | — | — | EP | disclosed |
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | Universite Paris-Saclay (FR) | 2021-06-15 | — | — | US | disclosed |
| US-11028249-B2 | Methods of synthesizing ionic liquids from primary alcohol-containing lignin compounds | NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) | 2021-06-08 | — | — | US | disclosed |
| US-20080113989-A1 | For example, N-(1-Carbamoyl-1-oxo-3-phenylpropan-2-yl)-2-(E-2-(4-(1-pyrrolidinylmethyl)phenyl)ethen-1-yl)benzamide; calcium channel blockers; cardiovascular disorders; antiarthritic agents; inhibitors of enzymes, especially cysteine proteases such as calpain and cathepsins | ABBVIE DEUTSCHLAND GMBH & CO KG (DE) | 2008-05-15 | — | — | US | disclosed |
| US-7276500-B2 | Calcium channel blockers; cardiovascular disorders; antiarthritic agents | ABBOTT GMBH & CO. KG (DE) | 2007-10-02 | — | — | US | disclosed |
| US-7276500-B2 | Calcium channel blockers; cardiovascular disorders; antiarthritic agents | ABBOTT GMBH & CO. KG (DE) | 2007-10-02 | — | — | US | disclosed |
| US-20070197508-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-23 | — | — | US | disclosed |
| US-20070197508-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-23 | — | — | US | disclosed |
| US-20070129351-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-07 | — | — | US | disclosed |
| US-20070129351-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-07 | — | — | US | disclosed |
| WO-2007053386-A2 | PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007053427-A2 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197508-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | HRH2, HRH4, HRH1 | HRH3 4/4885TSHR 463/4885MAPK1 3455/4885 |
| US-11028249-B2 | Methods of synthesizing ionic liquids from primary alcohol-containing lignin compounds | ADH1C, ADH5, ADH1A | HRH3 3842/4885TSHR 4765/4885MAPK1 1991/4885 |
| US-11034646-B2 | Method for the synthesis of unsymmetrical tertiary amines | ADH1C, PNMT, ADH1A | HRH3 88/4885TSHR 1103/4885MAPK1 2759/4885 |
| US-20070129351-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | HRH4, HRH2, HRH1 | HRH3 4/4885TSHR 375/4885MAPK1 3408/4885 |
| US-20080113989-A1 | For example, N-(1-Carbamoyl-1-oxo-3-phenylpropan-2-yl)-2-(E-2-(4-(1-pyrrolidinylmethyl)phenyl)ethen-1-yl)benzamide; calcium channel blockers; cardiovascular disorders; antiarthritic agents; inhibitors of enzymes, especially cysteine proteases such as calpain and cathepsins | CAPN1, CAPNS1, CAPN2 | HRH3 4432/4885TSHR 4029/4885MAPK1 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.