Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465229 | 0.89 | LMNA (0.63) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL14532784 | 0.89 | LMNA (0.63) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL6539801 | 0.89 | LMNA (0.63) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL30454910 | 0.88 | PPARG (0.55) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL2789840 | 0.87 | PPARG (0.54) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL2617240 | 0.87 | PPARG (0.54) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL2789835 | 0.87 | PPARG (0.54) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL2617242 | 0.86 | PPARG (0.51) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL30454282 | 0.85 | PPARG (0.50) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL17728765 | 0.85 | PPARG (0.58) | PPARGPPARAATMLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090246130-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246130-A1 | Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, TFRC, F13A1 | PPARG 4461/4885PPARA 4677/4885ATM 4510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.