Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ATIC | P31939 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1110383 | 0.92 | ACLY (0.48) | CYP2C9ATICCYP2C19HSD17B10MEN1 | |
| SCHEMBL1110258 | 0.82 | ACLY (0.58) | CYP2C9ATICCYP2C19HSD17B10MEN1 | |
| SCHEMBL1110309 | 0.82 | ACLY (0.49) | CYP2C9ATICCYP2C19HSD17B10ACLY | |
| SCHEMBL13658789 | 0.80 | CHEK2 (0.45) | ATICALDH1A1GAAPGRAKR1C3 | |
| SCHEMBL1320440 | 0.79 | ACLY (0.49) | CYP2C9ATICCYP2C19HSD17B10ACLY | |
| SCHEMBL13658687 | 0.76 | TUBB (0.41) | MEN1KMT2A | |
| SCHEMBL13658722 | 0.75 | CYP2C9 (0.60) | CYP2C9ATICCYP2C19HSD17B10ACLY | |
| SCHEMBL1320525 | 0.74 | KCNA5 (0.52) | MEN1KMT2AACLYALDH1A1PGR | |
| SCHEMBL13905620 | 0.74 | TUBB (0.48) | CYP2C9ATICCYP2C19HSD17B10MEN1 | |
| SCHEMBL1110473 | 0.73 | PGR (0.47) | CYP2C9ATICCYP2C19HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127723-A1 | NEW ARYLSULPHONYLGLYCINE DERIVATIVES, THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-22 | — | — | WO | disclosed |