Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18305639 | 0.86 | GPR6 (0.36) | — | |
| SCHEMBL13914989 | 0.86 | GPR6 (0.36) | — | |
| SCHEMBL1142207 | 0.80 | TRPV4 (0.35) | — | |
| SCHEMBL18305797 | 0.79 | TRPV4 (0.34) | — | |
| SCHEMBL4229118 | 0.75 | HTR1A (0.46) | HTR1ASLC6A2SLC6A3HRH1SLC6A4 | |
| SCHEMBL225826 | 0.75 | SLC6A2 (0.49) | HTR1ASLC6A2SLC6A3HRH1SLC6A4 | |
| SCHEMBL3130228 | 0.74 | SLC6A2 (0.50) | HTR1ASLC6A2SLC6A3HRH1SLC6A4 | |
| SCHEMBL31336126 | 0.74 | TRPV4 (0.35) | SLC6A4 | |
| SCHEMBL26076211 | 0.74 | TRPV4 (0.35) | SLC6A4 | |
| SCHEMBL4413610 | 0.73 | CTSL (0.41) | CSNK2A2CSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009129938-A1 | SUBSTITUTED PHENOXYBENZAMIDES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-10-29 | — | — | WO | disclosed |