Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177975 | 0.88 | MAOB (0.31) | — | |
| SCHEMBL13660725 | 0.88 | SMN1; SMN2 (0.41) | PGRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13660729 | 0.82 | PGR (0.43) | PGRSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL16749152 | 0.82 | FFAR2 (0.37) | — | |
| SCHEMBL10006447 | 0.82 | FFAR2 (0.37) | — | |
| SCHEMBL10006480 | 0.82 | AAK1 (0.34) | SMN1; SMN2LMNA | |
| SCHEMBL10006261 | 0.81 | AAK1 (0.33) | TP53LMNA | |
| SCHEMBL10006603 | 0.81 | AAK1 (0.33) | SMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL11932122 | 0.81 | AAK1 (0.33) | SMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL10006232 | 0.80 | TRPV1 (0.36) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009127338-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-10-22 | — | — | WO | disclosed |