Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13661141 | 0.94 | NPC1 (0.49) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL13661596 | 0.89 | SIGMAR1 (0.46) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL21120476 | 0.89 | SMN1; SMN2 (0.55) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL13661326 | 0.84 | CCR6 (0.48) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL13661586 | 0.84 | NPC1 (0.48) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL13661448 | 0.83 | SIGMAR1 (0.46) | KDM4EALDH1A1NPY1RNPC1RAB9A | |
| SCHEMBL13660815 | 0.83 | HTR7 (0.44) | SIGMAR1HRH3 | |
| SCHEMBL13661335 | 0.81 | CCR6 (0.51) | KDM4EALDH1A1CCR6PAX8MEN1 | |
| SCHEMBL9942494 | 0.80 | CCR6 (0.57) | ALDH1A1L3MBTL1CCR6PAX8KMT2A | |
| SCHEMBL4283767 | 0.79 | HRH3 (0.56) | KDM4EALDH1A1NPY1RNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |