Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13661596 | 0.91 | SIGMAR1 (0.46) | SIGMAR1HRH3 | |
| SCHEMBL13661448 | 0.85 | SIGMAR1 (0.46) | HTR7SIGMAR1TMEM97HTR1ACHRM5 | |
| SCHEMBL13661589 | 0.84 | CCR6 (0.51) | HTR7SIGMAR1TMEM97HTR1ACHRM5 | |
| SCHEMBL13661141 | 0.84 | NPC1 (0.49) | SIGMAR1HRH3 | |
| SCHEMBL13661574 | 0.83 | CCR6 (0.50) | HTR7SIGMAR1TMEM97HTR1ACHRM5 | |
| SCHEMBL13660817 | 0.83 | KDM4E (0.52) | SIGMAR1HRH3 | |
| SCHEMBL13660801 | 0.83 | OPRM1 (0.49) | SIGMAR1CCR5 | |
| SCHEMBL13660806 | 0.81 | OPRM1 (0.47) | SIGMAR1TMEM97HRH3CCR5 | |
| SCHEMBL13661326 | 0.79 | CCR6 (0.48) | HTR7SIGMAR1TMEM97HTR1ACHRM5 | |
| Hydrochloric Acid SCHEMBL23354635 | 0.79 | SIGMAR1 (0.47) | SIGMAR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |