Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP4 | P49662 | 1/20 | 0.36 |
| ▸ | CASP5 | P51878 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47050 | 0.92 | CHRM5 (0.67) | CHRM5ADRA2CACHECACNA2D1CACNA1B | |
| Hydrochloric Acid SCHEMBL4382180 | 0.90 | CHRM5 (0.64) | CHRM5ADRA2CACHECACNA2D1CACNA1B | |
| SCHEMBL528918 | 0.90 | CHRM5 (0.62) | CHRM5ADRA2CACHECACNA2D1CACNA1B | |
| Hydrochloric Acid SCHEMBL3551950 | 0.88 | CHRM5 (0.60) | CHRM5ADRA2CACHECACNA2D1CACNA1B | |
| Hydrochloric Acid SCHEMBL28737630 | 0.88 | CHRM5 (0.60) | CHRM5ADRA2CACHECACNA2D1CACNA1B | |
| SCHEMBL13660823 | 0.86 | CHRM5 (0.50) | CHRM5ADRA2CACHECACNA2D1CACNA1B | |
| SCHEMBL3062251 | 0.86 | CHRM5 (0.56) | CHRM5ADRA2CACHECACNA2D1CACNA1B | |
| SCHEMBL14422030 | 0.85 | GBA1 (0.48) | CHRM5ADRA2CACHECACNA2D1CACNA1B | |
| SCHEMBL13660827 | 0.85 | GNAO1 (0.46) | CHRM5ADRA2CRAD52GNAO1HRH3 | |
| SCHEMBL22297169 | 0.84 | GNAO1 (0.46) | CHRM5ADRA2CACHECACNA2D1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |