Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13661478 | 0.98 | GNAO1 (0.45) | GNAO1CYP1A2RAD52GNAI3GNAI1 | |
| SCHEMBL42348 | 0.96 | GNAO1 (0.49) | GNAO1CYP1A2RAD52GNAI3GNAI1 | |
| Hydrochloric Acid SCHEMBL4424002 | 0.94 | GNAO1 (0.51) | GNAO1CYP1A2RAD52GNAI3GNAI1 | |
| SCHEMBL640737 | 0.94 | GNAO1 (0.50) | GNAO1CYP1A2RAD52GNAI3GNAI1 | |
| Hydrochloric Acid SCHEMBL6150599 | 0.92 | GNAO1 (0.53) | GNAO1CYP1A2RAD52GNAI3GNAI1 | |
| SCHEMBL3440711 | 0.90 | GNAO1 (0.50) | GNAO1CYP1A2RAD52GNAI3GNAI1 | |
| SCHEMBL13660823 | 0.86 | CHRM5 (0.50) | GNAO1CYP1A2RAD52GNAI3GNAI1 | |
| SCHEMBL7122133 | 0.85 | GNAO1 (0.54) | GNAO1RAD52GNAI3GNAI1CXCR4 | |
| SCHEMBL13660822 | 0.85 | CHRM5 (0.57) | GNAO1RAD52CHRM5ADRA2CCXCR4 | |
| SCHEMBL7462427 | 0.85 | CYP1A2 (0.43) | GNAO1CYP1A2RAD52GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |