Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20215706 | 0.91 | GNAO1 (0.43) | CHRM5ADRA2CGNAO1ACHECYP1A2 | |
| SCHEMBL42348 | 0.89 | GNAO1 (0.49) | CHRM5ADRA2CGNAO1CYP1A2GNAI3 | |
| Hydrochloric Acid SCHEMBL4424002 | 0.88 | GNAO1 (0.51) | CHRM5ADRA2CGNAO1CYP1A2GNAI3 | |
| SCHEMBL640737 | 0.88 | GNAO1 (0.50) | CHRM5ADRA2CGNAO1CYP1A2GNAI3 | |
| SCHEMBL13660822 | 0.86 | CHRM5 (0.57) | CHRM5ADRA2CGNAO1ACHESMN1; SMN2 | |
| SCHEMBL13660827 | 0.86 | GNAO1 (0.46) | CHRM5ADRA2CGNAO1CYP1A2GNAI3 | |
| SCHEMBL27097471 | 0.86 | CHRM5 (0.69) | CHRM5ADRA2CACHECYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6150599 | 0.86 | GNAO1 (0.53) | CHRM5ADRA2CGNAO1CYP1A2GNAI3 | |
| SCHEMBL47050 | 0.86 | CHRM5 (0.67) | CHRM5ADRA2CGNAO1ACHESMN1; SMN2 | |
| SCHEMBL13661478 | 0.84 | GNAO1 (0.45) | CHRM5ADRA2CGNAO1CYP1A2GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009131246-A1 | SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | ASTELLAS PHARMA INC. (JP) | 2009-10-29 | — | — | WO | disclosed |