SCHEMBL1366287

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1366284	1.00	JAK2 (0.48)	JAK2JAK1TYK2JAK3NTRK1
	SCHEMBL1366228	0.91	JAK2 (0.50)	JAK2JAK1TYK2JAK3NTRK1
	SCHEMBL1366234	0.91	JAK2 (0.50)	JAK2JAK1TYK2JAK3NTRK1
	SCHEMBL1367484	0.90	JAK2 (0.49)	JAK2JAK1TYK2JAK3NTRK1
	SCHEMBL1367481	0.90	JAK2 (0.49)	JAK2JAK1TYK2JAK3NTRK1
	SCHEMBL1368009	0.89	JAK2 (0.48)	JAK2JAK1TYK2JAK3NTRK1
	SCHEMBL1368004	0.89	JAK2 (0.48)	JAK2JAK1TYK2JAK3NTRK1
	SCHEMBL1367031	0.89	JAK2 (0.51)	JAK2JAK1TYK2JAK3NTRK1
	SCHEMBL1367027	0.89	JAK2 (0.51)	JAK2JAK1TYK2JAK3NTRK1
	SCHEMBL1368144	0.88	JAK2 (0.46)	JAK2JAK1TYK2JAK3NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.