Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.52 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759552 | 0.85 | KCNH2 (0.66) | KCNH2RIOK2MEN1KMT2AALDH1A1 | |
| SCHEMBL11759545 | 0.85 | KCNH2 (0.66) | KCNH2RIOK2MEN1KMT2AALDH1A1 | |
| SCHEMBL13662907 | 0.84 | ALDH1A1 (0.50) | KCNH2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13662902 | 0.81 | KCNH2 (0.52) | KCNH2RIOK2MEN1KMT2ANPC1 | |
| SCHEMBL13662910 | 0.79 | ALDH1A1 (0.44) | KCNH2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4343601 | 0.79 | KCNH2 (0.64) | KCNH2RIOK2MEN1KMT2ANPC1 | |
| SCHEMBL4343598 | 0.79 | KCNH2 (0.64) | KCNH2RIOK2MEN1KMT2ANPC1 | |
| SCHEMBL13662890 | 0.76 | KCNH2 (0.55) | KCNH2RIOK2MEN1KMT2AALDH1A1 | |
| SCHEMBL20280214 | 0.76 | KCNH2 (0.50) | KCNH2RIOK2MEN1KMT2ANPC1 | |
| SCHEMBL13662908 | 0.76 | KCNH2 (0.56) | KCNH2RIOK2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090269543-A1 | OPTICAL RECORDING MEDIUM | TDK CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| US-20090269543-A1 | OPTICAL RECORDING MEDIUM | TDK CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| US-20090226658-A1 | Optical Recording Medium | TDK CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090226658-A1 | Optical Recording Medium | TDK CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
| US-20090149660-A1 | OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIA | TDK CORPORATION (JP) | 2009-06-11 | — | — | US | disclosed |
| US-20090149660-A1 | OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIA | TDK CORPORATION (JP) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149660-A1 | OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIA | KCNN4, CACNA1E, KCNN2 | KCNH2 6/4885RIOK2 1997/4885MEN1 414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.