Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 14/20 | 0.66 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11759545 | 1.00 | KCNH2 (0.66) | KCNH2RIOK2EGFRALDH1A1TSHR | |
| SCHEMBL13662908 | 0.89 | KCNH2 (0.56) | KCNH2RIOK2EGFRALDH1A1TSHR | |
| SCHEMBL11414578 | 0.88 | KCNH2 (0.62) | KCNH2RIOK2EGFRALDH1A1TSHR | |
| SCHEMBL11414575 | 0.88 | KCNH2 (0.62) | KCNH2RIOK2EGFRALDH1A1TSHR | |
| SCHEMBL13662902 | 0.85 | KCNH2 (0.52) | KCNH2RIOK2ALDH1A1TSHRALOX15 | |
| SCHEMBL13662906 | 0.85 | KCNH2 (0.52) | KCNH2RIOK2ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL20280048 | 0.85 | KCNH2 (0.59) | KCNH2RIOK2EGFRALDH1A1TSHR | |
| SCHEMBL29914719 | 0.83 | KCNH2 (0.50) | KCNH2RIOK2ALDH1A1TSHRALOX15 | |
| SCHEMBL90533 | 0.83 | KCNH2 (0.50) | KCNH2RIOK2ALDH1A1TSHRALOX15 | |
| SCHEMBL13662921 | 0.82 | KCNH2 (0.58) | KCNH2RIOK2ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055567-A | Preparation of o,o'-dihydroxyazobenzenes from o-nitrophenols | PHILLIPS PETROLEUM COMPANY (US) | 1977-10-25 | — | — | US | claimed |
| US-4055567-A | Preparation of o,o'-dihydroxyazobenzenes from o-nitrophenols | PHILLIPS PETROLEUM COMPANY (US) | 1977-10-25 | — | — | US | disclosed |