SCHEMBL13662902

SCHEMBL13662902

CN(C)c1ccc(N=Nc2cc(Cl)ccc2O)c(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 13/20 0.52
L3MBTL1 Q9Y468 2/20 0.51
CASP3 P42574 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
RIOK2 Q9BVS4 1/20 0.46
NPC1 O15118 2/20 0.41
MEN1 O00255 2/20 0.41
MAPK1 P28482 2/20 0.41
KMT2A Q03164 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.39
NSD2 O96028 1/20 0.37
MMP14 P50281 1/20 0.37
CASP6 P55212 1/20 0.37
HSD17B10 Q99714 2/20 0.37
KDM4E B2RXH2 1/20 0.37
RGS12 O14924 1/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13662908 0.92 KCNH2 (0.56) KCNH2L3MBTL1CASP3SENP7SENP6
SCHEMBL11759545 0.85 KCNH2 (0.66) KCNH2RIOK2MEN1MAPK1KMT2A
SCHEMBL11759552 0.85 KCNH2 (0.66) KCNH2RIOK2MEN1MAPK1KMT2A
SCHEMBL13662903 0.84 L3MBTL1 (0.48) KCNH2L3MBTL1CASP3SENP7SENP6
SCHEMBL13662906 0.81 KCNH2 (0.52) KCNH2RIOK2NPC1MEN1MAPK1
SCHEMBL13662904 0.79 NR1H2 (0.48) KCNH2L3MBTL1CASP3SENP7SENP6
SCHEMBL11624172 0.79 CASP3 (0.74) L3MBTL1CASP3SENP7SENP6NPC1
SCHEMBL11624176 0.79 CASP3 (0.74) L3MBTL1CASP3SENP7SENP6NPC1
SCHEMBL10604052 0.79 KCNH2 (0.64) KCNH2RIOK2MEN1KMT2AMAPT
SCHEMBL11694049 0.78 L3MBTL1 (0.59) L3MBTL1CASP3SENP7SENP6NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090269543-A1 OPTICAL RECORDING MEDIUM TDK CORPORATION (JP) 2009-10-29 US disclosed
US-20090269543-A1 OPTICAL RECORDING MEDIUM TDK CORPORATION (JP) 2009-10-29 US disclosed
US-20090226658-A1 Optical Recording Medium TDK CORPORATION (JP) 2009-09-10 US disclosed
US-20090226658-A1 Optical Recording Medium TDK CORPORATION (JP) 2009-09-10 US disclosed
US-20090149660-A1 OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIA TDK CORPORATION (JP) 2009-06-11 US disclosed
US-20090149660-A1 OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIA TDK CORPORATION (JP) 2009-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149660-A1 OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIA KCNN4, CACNA1E, KCNN2 KCNH2 6/4885L3MBTL1 2725/4885CASP3 2737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.