Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.74 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.71 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.71 |
| ▸ | TTR | P02766 | 1/20 | 0.71 |
| ▸ | MGAM | O43451 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.60 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demethylxanthohumol SCHEMBL1023989 | 0.88 | MGAM (0.81) | ABCB1ALOX5PDPK1TTRMGAM | |
| Demethylxanthohumol SCHEMBL31051585 | 0.88 | MGAM (0.81) | ABCB1ALOX5PDPK1TTRMGAM | |
| Demethylxanthohumol SCHEMBL4834910 | 0.88 | MGAM (0.81) | ABCB1ALOX5PDPK1TTRMGAM | |
| SCHEMBL26539037 | 0.86 | PDPK1 (0.93) | ABCB1ALOX5PDPK1TTRMGAM | |
| SCHEMBL30630210 | 0.86 | PDPK1 (0.93) | ABCB1ALOX5PDPK1TTRMGAM | |
| SCHEMBL5519605 | 0.85 | ABCB1 (1.00) | ABCB1ALOX5PDPK1TTRTDP1 | |
| SCHEMBL5519601 | 0.85 | ABCB1 (1.00) | ABCB1ALOX5PDPK1TTRTDP1 | |
| SCHEMBL4831492 | 0.84 | ABCB1 (0.74) | ABCB1ALOX5PDPK1TTRCYP19A1 | |
| SCHEMBL4831500 | 0.84 | ABCB1 (0.74) | ABCB1ALOX5PDPK1TTRCYP19A1 | |
| Xanthogalenol SCHEMBL4837290 | 0.83 | PDPK1 (0.84) | ABCB1ALOX5PDPK1TTRMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090270423-A1 | ANTIBACTERIAL SMALL MOLECULES AND METHODS FOR THEIR SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2009-10-29 | — | — | US | disclosed |
| US-20090270423-A1 | ANTIBACTERIAL SMALL MOLECULES AND METHODS FOR THEIR SYNTHESIS | NATIONAL SCIENCE FOUNDATION | 2009-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270423-A1 | ANTIBACTERIAL SMALL MOLECULES AND METHODS FOR THEIR SYNTHESIS | CLSPN, FDPS, DHPS | ABCB1 227/4885ALOX5 2114/4885PDPK1 2139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.