Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 18/20 | 1.00 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.73 |
| ▸ | TTR | P02766 | 1/20 | 0.73 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5519605 | 1.00 | ABCB1 (1.00) | ABCB1PDPK1TTRALOX5TDP1 | |
| SCHEMBL144848 | 0.92 | ABCB1 (0.85) | ABCB1PDPK1TTRALOX5 | |
| SCHEMBL17585476 | 0.91 | ABCB1 (0.84) | ABCB1PDPK1TTRALOX5 | |
| SCHEMBL16166211 | 0.90 | ABCB1 (1.00) | ABCB1PDPK1TTRALOX5 | |
| SCHEMBL16166208 | 0.90 | ABCB1 (1.00) | ABCB1PDPK1TTRALOX5 | |
| SCHEMBL26539037 | 0.87 | PDPK1 (0.93) | ABCB1PDPK1TTRALOX5 | |
| SCHEMBL30630210 | 0.87 | PDPK1 (0.93) | ABCB1PDPK1TTRALOX5 | |
| SCHEMBL13663232 | 0.85 | ABCB1 (0.74) | ABCB1PDPK1TTRALOX5TDP1 | |
| SCHEMBL4831500 | 0.85 | ABCB1 (0.74) | ABCB1PDPK1TTRALOX5TDP1 | |
| SCHEMBL4831492 | 0.85 | ABCB1 (0.74) | ABCB1PDPK1TTRALOX5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | claimed |
| EP-1623704-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-08 | — | — | EP | claimed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| US-20070092551-A1 | Therapeutic agent | TAKARA BIO INC. (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1623704-A1 | THERAPEUTIC AGENT | TAKARA BIO INC. (JP) | 2006-02-08 | — | — | EP | disclosed |
| US-5234951-A | Anti-ulcer agent comprising chalcone derivative | TSUMURA JUNTENDO, INC. (JP) | 1993-08-10 | — | — | US | disclosed |
| US-5106871-A | Reduced side effects | TSUMURA & CO. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0292576-A1 | ANTI-ULCEROUS AGENT CONTAINING CHALCONE DERIVATIVE AS EFFECTIVE INGREDIENT AND NOVEL CHALCONE DERIVATIVES | TSUMURA & CO. (JP) | 1988-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070092551-A1 | Therapeutic agent | FABP4, GPR119, IAPP | ABCB1 2586/4885PDPK1 312/4885TTR 838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.