SCHEMBL13664000

SCHEMBL13664000

O=c1ccn([C@@H]2C=C(CO)[C@H](O)C2)c(=O)[nH]1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.48
SLC28A2 O43868 1/20 0.48
SLC29A1 Q99808 1/20 0.48
SLC28A3 Q9HAS3 1/20 0.48
P2RY2 P41231 13/20 0.43
DUT P33316 2/20 0.40
P2RY6 Q15077 9/20 0.38
P2RY4 P51582 5/20 0.37
P2RY14 Q15391 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19052706 0.80 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL19052786 0.80 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL19053005 0.80 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL10470783 0.80 DUT (0.42) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL22902121 0.73 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL12280146 0.73 SLC28A1 (0.52) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL13664001 0.73 LMNA (0.50) SLC29A1P2RY2
SCHEMBL8885780 0.72 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL14928767 0.72 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL12157247 0.71 SLC28A1 (0.47) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090270431-A1 Cyclopentenol Nucleoside Compounds Intermediates for their Synthesis and Methods of Treating Viral Infections THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) 2009-10-29 US disclosed
WO-2007047793-A2 CYCLOPENTENOL NUCLEOSIDE COMPOUNDS, INTERMEDIATES FOR THEIR SYNTHESIS AND METHODS OF TREATING VIRAL INFECTIONS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270431-A1 Cyclopentenol Nucleoside Compounds Intermediates for their Synthesis and Methods of Treating Viral Infections REV1, NSUN2, ORC3 SLC28A1 281/4885SLC28A2 240/4885SLC29A1 120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.