Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 6/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891135 | 0.75 | LMNA (0.43) | GRIN1GRIN2BKCNH2TSHRABL1 | |
| SCHEMBL11435922 | 0.74 | DRD3 (0.48) | GRIN1GRIN2BKCNH2ABL1DHFR | |
| SCHEMBL10887063 | 0.73 | KDM4E (0.54) | GRIN1GRIN2BKCNH2TSHRABL1 | |
| Hydrochloric Acid SCHEMBL11442762 | 0.73 | DRD3 (0.47) | GRIN1GRIN2BKCNH2ABL1DHFR | |
| SCHEMBL13664887 | 0.70 | KCNH2 (0.41) | GRIN1GRIN2BKCNH2DHFRMAPT | |
| SCHEMBL11434275 | 0.70 | ABL1 (0.49) | GRIN1GRIN2BKCNH2ABL1DHFR | |
| SCHEMBL10893197 | 0.70 | MEN1 (0.45) | GRIN1GRIN2BKCNH2ABL1DHFR | |
| SCHEMBL11935745 | 0.69 | GRIA1 (0.53) | GRIN1GRIN2BKCNH2ABL1DHFR | |
| SCHEMBL6950384 | 0.69 | ABL1 (0.63) | GRIN1GRIN2BKCNH2ABL1DHFR | |
| SCHEMBL11110739 | 0.69 | ALDH1A1 (0.51) | GRIN1GRIN2BKCNH2ABL1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |