Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664708 | 0.81 | LMNA (0.42) | SLC6A2SLC6A3 | |
| SCHEMBL512106 | 0.77 | SRD5A1 (0.41) | HTR3ASLC2A1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL13664736 | 0.76 | HTR2A (0.43) | HTR3ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL15874655 | 0.75 | KDM4E (0.42) | HTR3ASLC2A1 | |
| SCHEMBL1616775 | 0.75 | KDM4E (0.42) | HTR3ASLC2A1 | |
| SCHEMBL11840693 | 0.74 | KMT2A (0.42) | HTR3A | |
| SCHEMBL13664822 | 0.73 | CYP19A1 (0.34) | — | |
| SCHEMBL15282087 | 0.72 | SRD5A1 (0.43) | HTR3ASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL13664705 | 0.72 | TSHR (0.39) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL18616622 | 0.71 | SLC6A3 (0.43) | HTR3ASLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |