Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18616622 | 0.91 | SLC6A3 (0.43) | LMNASLC6A3SLC6A2GAAHTT | |
| SCHEMBL13664709 | 0.81 | HTR3A (0.46) | SLC6A3SLC6A2 | |
| SCHEMBL5556432 | 0.78 | LMNA (0.46) | LMNASLC6A3SLC6A2GAAHTT | |
| SCHEMBL13664736 | 0.74 | HTR2A (0.43) | SLC6A3SLC6A2TP53ALDH1A1TSHR | |
| SCHEMBL13664705 | 0.73 | TSHR (0.39) | SLC6A3SLC6A2GAADRD2ALDH1A1 | |
| SCHEMBL3695746 | 0.73 | DRD2 (0.62) | SLC6A3SLC6A2DRD2 | |
| SCHEMBL13664822 | 0.72 | CYP19A1 (0.34) | DRD2 | |
| Fumaric Acid SCHEMBL28748009 | 0.70 | SLC6A2 (0.50) | SLC6A3SLC6A2DRD2 | |
| SCHEMBL2410760 | 0.68 | HTR3A (0.62) | SLC6A3SLC6A2DRD2 | |
| SCHEMBL6178562 | 0.68 | CHRNB2 (0.53) | SLC6A3SLC6A2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |