Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.58 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | CYBB | P04839 | 2/20 | 0.36 |
| ▸ | NOX5 | Q96PH1 | 2/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664823 | 0.84 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL13664710 | 0.78 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL13664702 | 0.78 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL13664863 | 0.74 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13664891 | 0.72 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL8306364 | 0.72 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3P2RX7 | |
| SCHEMBL20203588 | 0.70 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3CXCR4 | |
| SCHEMBL8560632 | 0.70 | HSD17B10 (0.46) | — | |
| SCHEMBL13664684 | 0.70 | SLC6A2 (0.91) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31537000 | 0.69 | SLC6A4 (0.51) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |