Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | CYBB | P04839 | 2/20 | 0.48 |
| ▸ | NOX5 | Q96PH1 | 2/20 | 0.48 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814949 | 0.90 | ADRB1 (0.56) | SLC6A2SLC6A4SLC6A3ADRB1CYBB | |
| Hydrochloric Acid SCHEMBL1663296 | 0.89 | ADRB1 (0.54) | SLC6A2SLC6A4SLC6A3ADRB1CYBB | |
| SCHEMBL13664823 | 0.85 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3ADRB1CYBB | |
| SCHEMBL13664710 | 0.82 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL25575696 | 0.79 | ADRB1 (0.49) | ADRB1CYBBNOX5NOX4NOX1 | |
| SCHEMBL5436101 | 0.78 | ALOX5 (0.54) | ALOX5P2RX7ALBADRA1DADRA1A | |
| SCHEMBL13664716 | 0.78 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL5480292 | 0.77 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3ADRB1ALOX5 | |
| SCHEMBL13664891 | 0.76 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL20103130 | 0.76 | ADRA1A (0.48) | ALOX5P2RX7ALBADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |