Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | CYBB | P04839 | 2/20 | 0.39 |
| ▸ | NOX5 | Q96PH1 | 2/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31537000 | 0.91 | SLC6A4 (0.51) | SLC6A2SLC6A4SLC6A3MAPTUSP2 | |
| SCHEMBL13664702 | 0.82 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3MAPTADRA1B | |
| SCHEMBL13664716 | 0.78 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3CXCR4CYBB | |
| SCHEMBL13664863 | 0.78 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3MAPTL3MBTL1 | |
| SCHEMBL13664742 | 0.78 | MAPT (0.50) | SLC6A2SLC6A4SLC6A3MAPTUSP2 | |
| SCHEMBL9982890 | 0.77 | NPSR1 (0.43) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL13664891 | 0.77 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CXCR4ALDH1A1 | |
| SCHEMBL13664823 | 0.74 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3MAPTMEN1 | |
| SCHEMBL13664684 | 0.73 | SLC6A2 (0.91) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13664888 | 0.72 | SLC6A2 (0.79) | SLC6A2SLC6A4SLC6A3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |