Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYBB | P04839 | 2/20 | 0.42 |
| ▸ | NOX5 | Q96PH1 | 2/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664702 | 0.85 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL13664716 | 0.84 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL2985382 | 0.82 | RECQL (0.54) | SLC6A2SLC6A4SLC6A3RECQLP2RX7 | |
| Acetic Acid SCHEMBL2981956 | 0.77 | RECQL (0.48) | RECQLP2RX7MEN1KMT2AHCAR1 | |
| SCHEMBL1814949 | 0.76 | ADRB1 (0.56) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| Hydrochloric Acid SCHEMBL1663296 | 0.75 | ADRB1 (0.54) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL13664745 | 0.75 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3RECQLP2RX7 | |
| SCHEMBL3658673 | 0.74 | P2RX7 (0.42) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL13664710 | 0.74 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3CYBBNOX5 | |
| SCHEMBL13664891 | 0.71 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CYBBNOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |