Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 4/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 7/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696190 | 0.92 | HDAC4 (0.56) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL29386619 | 0.92 | HDAC4 (0.56) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL19932068 | 0.86 | SMN1; SMN2 (0.52) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL29384053 | 0.85 | HDAC4 (0.52) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL29696206 | 0.85 | HDAC4 (0.52) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL13664813 | 0.84 | SMN1; SMN2 (0.69) | HDAC4HDAC1CTSKCTSSSMN1; SMN2 | |
| SCHEMBL23483309 | 0.83 | CTSK (0.55) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL26436622 | 0.82 | HDAC4 (0.65) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL23454631 | 0.82 | HDAC4 (0.65) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL19931848 | 0.80 | HDAC4 (0.49) | HDAC4HDAC1HDAC3HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |