Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.56 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.51 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789654 | 0.87 | EGFR (0.54) | SMN1; SMN2EGFRAAK1MAP1LC3BMAP1LC3A | |
| SCHEMBL13664730 | 0.84 | HDAC4 (0.54) | SMN1; SMN2EGFRCTSSCTSKCA12 | |
| SCHEMBL30135035 | 0.83 | EGFR (0.55) | SMN1; SMN2EGFRAAK1MAP1LC3BMAP1LC3A | |
| SCHEMBL9490468 | 0.82 | AAK1 (0.62) | SMN1; SMN2EGFRAAK1MAP1LC3BMAP1LC3A | |
| SCHEMBL30340914 | 0.82 | ALDH1A1 (0.58) | SMN1; SMN2EGFRCTSSCTSKMEN1 | |
| SCHEMBL26503173 | 0.82 | ALDH1A1 (0.58) | SMN1; SMN2EGFRCTSSCTSKMEN1 | |
| SCHEMBL30134945 | 0.82 | AAK1 (0.69) | EGFRAAK1MAP1LC3BMAP1LC3ACTSL | |
| SCHEMBL13664903 | 0.82 | ALDH1A1 (0.58) | SMN1; SMN2EGFRCTSSCTSKMEN1 | |
| SCHEMBL30135089 | 0.82 | AAK1 (0.60) | SMN1; SMN2EGFRAAK1MAP1LC3BMAP1LC3A | |
| SCHEMBL29462332 | 0.82 | CTSL (0.54) | SMN1; SMN2AAK1CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |