Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.60 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8306961 | 0.92 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3BRD9F10 | |
| SCHEMBL8305752 | 0.81 | THRB (0.43) | SLC6A2SLC6A4SLC6A3ALDH1A1NPC1 | |
| SCHEMBL7806456 | 0.81 | BRD9 (0.53) | BRD9ALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL8267983 | 0.80 | BRD9 (0.59) | BRD9F10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8312046 | 0.78 | BRD9 (0.58) | BRD9F10ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1583560 | 0.78 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3F10 | |
| SCHEMBL9881483 | 0.77 | ADRB1 (0.46) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1583620 | 0.77 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3F10 | |
| SCHEMBL13664863 | 0.75 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3MAPTSMN1; SMN2 | |
| SCHEMBL8257893 | 0.75 | ALDH1A1 (0.42) | ALDH1A1NPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |