Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13665093 | 0.87 | TSHR (0.61) | TSHRKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL13664758 | 0.85 | TSHR (0.65) | TSHRKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL20800915 | 0.77 | KDM4E (0.68) | TSHRKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL18424429 | 0.75 | KDM4E (0.78) | TSHRKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL13664754 | 0.72 | TAAR1 (0.54) | KDM4EALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL30162579 | 0.72 | IL4I1 (0.49) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL6521139 | 0.72 | IL4I1 (0.49) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL13664838 | 0.70 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL13664590 | 0.69 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10MAPTHPGD | |
| SCHEMBL13664841 | 0.68 | KDM4E (0.68) | KDM4EALDH1A1HSD17B10MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009128262-A1 | QUINOLONE DERIVATIVE AND USE THEREOF | 武田薬品工業株式会社 (JP) | 2009-10-22 | — | — | WO | disclosed |