Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664819 | 0.80 | STK17B (0.52) | HTTLMNA | |
| SCHEMBL13664868 | 0.80 | STK17B (0.55) | HTTLMNAMAPTMEN1KMT2A | |
| SCHEMBL13664796 | 0.78 | MEN1 (0.40) | HTTLMNATSHRPOLBMAPT | |
| SCHEMBL13665284 | 0.77 | AAK1 (0.43) | HTTLMNAPOLBMAPTMEN1 | |
| SCHEMBL1105702 | 0.76 | PCSK9 (0.50) | PCSK9LMNAMEN1KMT2AAAK1 | |
| SCHEMBL13664688 | 0.76 | KMT2A (0.42) | HTTLMNATSHRPOLBMAPT | |
| SCHEMBL19932072 | 0.75 | EGFR (0.57) | HTTLMNAPOLBMAPTMEN1 | |
| SCHEMBL30524647 | 0.75 | F2R (0.43) | HTTLMNATSHRHPGDCYP3A4 | |
| SCHEMBL13664865 | 0.75 | ITGB1 (0.36) | HTTLMNATSHRPOLBMAPT | |
| SCHEMBL16303890 | 0.75 | EPHX1 (0.58) | HTTLMNAPOLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |