Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13664819 | 0.78 | STK17B (0.52) | DRD2LMNAHTTIDO1 | |
| SCHEMBL13664868 | 0.78 | STK17B (0.55) | KMT2ADRD2MEN1LMNAHTT | |
| SCHEMBL13664796 | 0.76 | MEN1 (0.40) | KMT2AMEN1LMNAHTTPOLB | |
| SCHEMBL13664899 | 0.76 | PCSK9 (0.48) | KMT2AMEN1LMNAHTTPOLB | |
| SCHEMBL13665292 | 0.74 | DRD2 (0.35) | KMT2AUSP2DRD2NPFFR1NPFFR2 | |
| SCHEMBL19932072 | 0.74 | EGFR (0.57) | KMT2AMEN1LMNAHTTPOLB | |
| SCHEMBL16303890 | 0.73 | EPHX1 (0.58) | KMT2AMEN1LMNAHTTPOLB | |
| SCHEMBL12118967 | 0.73 | LMNA (0.70) | KMT2AMEN1LMNAHTTPOLB | |
| SCHEMBL6381128 | 0.72 | SLC6A4 (0.50) | DRD2 | |
| SCHEMBL21726289 | 0.72 | SLC6A4 (0.44) | DRD2NPFFR1NPFFR2IDO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |