Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18497963 | 0.86 | OPRD1 (0.44) | OPRD1OPRK1HDAC1HDAC6HDAC8 | |
| SCHEMBL12447685 | 0.83 | OPRD1 (0.51) | OPRD1OPRK1HDAC1HDAC6HDAC8 | |
| SCHEMBL8293418 | 0.83 | OPRD1 (0.47) | OPRD1OPRK1HDAC1HDAC6HDAC8 | |
| SCHEMBL1049753 | 0.82 | HDAC1 (0.50) | OPRD1OPRK1HDAC1HDAC6CYP2D6 | |
| SCHEMBL17685968 | 0.81 | OPRD1 (0.45) | OPRD1OPRK1HDAC1HDAC6HDAC8 | |
| SCHEMBL327031 | 0.80 | L3MBTL1 (0.47) | OPRD1OPRK1HDAC1HDAC6TP53 | |
| SCHEMBL31070004 | 0.79 | HDAC1 (0.41) | OPRD1OPRK1HDAC1HDAC6HDAC8 | |
| SCHEMBL2381460 | 0.79 | CYP2D6 (0.59) | SCD5CYP2D6CYP3A4TSHRCYP1A2 | |
| SCHEMBL24718689 | 0.78 | RIPK1 (0.65) | OPRD1OPRK1HDAC1HDAC6HDAC8 | |
| SCHEMBL16862352 | 0.77 | OPRD1 (0.52) | OPRD1OPRK1HDAC1HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119528-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |