Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Dimethoxybenzene SCHEMBL901285 | 0.81 | ACHE (0.70) | ACHESMN1; SMN2CYP3A4ALDH1A1CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL9350 | 0.81 | ACHE (0.70) | ACHESMN1; SMN2CYP3A4ALDH1A1CA1 | |
| SCHEMBL535411 | 0.80 | ACHE (0.52) | ACHESMN1; SMN2CYP3A4ALDH1A1CA1 | |
| SCHEMBL13480728 | 0.78 | ACHE (0.50) | ACHESMN1; SMN2CYP3A4ALDH1A1CA1 | |
| SCHEMBL98036 | 0.78 | ACHE (0.50) | ACHESMN1; SMN2CYP3A4ALDH1A1CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL7860661 | 0.78 | ACHE (0.67) | ACHESMN1; SMN2CYP3A4ALDH1A1CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL28343465 | 0.78 | ACHE (0.67) | ACHESMN1; SMN2CYP3A4ALDH1A1CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL28542304 | 0.78 | ACHE (0.67) | ACHESMN1; SMN2CYP3A4ALDH1A1CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL15870025 | 0.78 | ACHE (0.67) | ACHESMN1; SMN2CYP3A4ALDH1A1CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL28068595 | 0.78 | ACHE (0.67) | ACHESMN1; SMN2CYP3A4ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847532-B1 | IGF-1R INHIBITOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-7605272-B2 | IGF-1R inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20090054508-A1 | IGF-1R INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054508-A1 | IGF-1R INHIBITOR | IGF1R, IGFBP5, IGFBP1 | ACHE 4528/4885SMN1; SMN2 3100/4885CYP3A4 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.