⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259247 | 0.75 | — | — | |
| SCHEMBL18469863 | 0.75 | — | — | |
| SCHEMBL12126320 | 0.74 | RAB9A (0.53) | — | |
| SCHEMBL4843604 | 0.73 | — | — | |
| SCHEMBL2642510 | 0.73 | — | — | |
| SCHEMBL14431689 | 0.73 | — | — | |
| SCHEMBL10531759 | 0.73 | — | — | |
| SCHEMBL6841098 | 0.72 | MAPT (0.62) | — | |
| SCHEMBL12128411 | 0.72 | FDPS (0.51) | — | |
| Hydrochloric Acid SCHEMBL7036884 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847532-B1 | IGF-1R INHIBITOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-7605272-B2 | IGF-1R inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-10-20 | — | — | US | disclosed |
| US-20090054508-A1 | IGF-1R INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |