Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13667380 | 1.00 | AVPR2 (0.42) | AVPR2AVPR1ACNR2POLBSIRT2 | |
| SCHEMBL4316123 | 0.86 | AVPR2 (0.45) | AVPR2AVPR1ACNR2CACNA2D1CACNA1B | |
| Cenobamate SCHEMBL1682643 | 0.82 | POLB (0.46) | AVPR2AVPR1APOLB | |
| Cenobamate SCHEMBL29410391 | 0.82 | POLB (0.46) | AVPR2AVPR1APOLB | |
| Cenobamate SCHEMBL13667363 | 0.82 | POLB (0.46) | AVPR2AVPR1APOLB | |
| Cenobamate SCHEMBL4308624 | 0.82 | POLB (0.46) | AVPR2AVPR1APOLB | |
| SCHEMBL4308060 | 0.82 | POLB (0.36) | AVPR2AVPR1APOLB | |
| SCHEMBL23307859 | 0.79 | ADRB1 (0.39) | — | |
| SCHEMBL4311442 | 0.79 | ADRB1 (0.39) | — | |
| SCHEMBL4312963 | 0.79 | KIF11 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598279-B2 | Neurotherapeutic azole compounds | SK HOLDINGS CO., LTD. (KR) | 2009-10-06 | — | — | US | disclosed |
| US-7598279-B2 | Neurotherapeutic azole compounds | SK HOLDINGS CO., LTD. (KR) | 2009-10-06 | — | — | US | disclosed |