SCHEMBL4308060

SCHEMBL4308060

Cc1ccccc1C(Cn1ncnn1)OC(N)=O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
ALDH1A1 P00352 1/20 0.33
NR3C2 P08235 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
PLA2G1B P04054 1/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
AVPR2 P30518 1/20 0.31
AVPR1A P37288 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cenobamate SCHEMBL29410391 0.85 POLB (0.46) POLBAVPR2AVPR1A
Cenobamate SCHEMBL4308624 0.85 POLB (0.46) POLBAVPR2AVPR1A
Cenobamate SCHEMBL1682643 0.85 POLB (0.46) POLBAVPR2AVPR1A
Cenobamate SCHEMBL13667363 0.85 POLB (0.46) POLBAVPR2AVPR1A
SCHEMBL4309040 0.85 NR3C2 (0.36) ALDH1A1NR3C2HPGDKMT2A
SCHEMBL13667380 0.82 AVPR2 (0.42) POLBAVPR2AVPR1A
SCHEMBL13667381 0.82 AVPR2 (0.42) POLBAVPR2AVPR1A
SCHEMBL23307859 0.82 ADRB1 (0.39)
SCHEMBL4311442 0.82 ADRB1 (0.39)
SCHEMBL4318298 0.80 POLB (0.33) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3556345-B1 ORALLY DISINTEGRATED TABLET COMPRISING CARBAMATE COMPOUND SK BIOPHARMACEUTICALS CO LTD (KR) 2021-09-22 EP disclosed
EP-3556345-A1 ORALLY DISINTEGRATED TABLET COMPRISING CARBAMATE COMPOUND SK Biopharmaceuticals Co., Ltd. (KR) 2019-10-23 EP disclosed
EP-1879873-B1 NEUROTHERAPEUTIC AZOLE COMPOUNDS SK BIOPHARMACEUTICALS CO LTD (KR) 2013-10-09 EP disclosed
US-7598279-B2 Neurotherapeutic azole compounds SK HOLDINGS CO., LTD. (KR) 2009-10-06 US disclosed
US-7598279-B2 Neurotherapeutic azole compounds SK HOLDINGS CO., LTD. (KR) 2009-10-06 US disclosed
US-7598279-B2 Neurotherapeutic azole compounds SK HOLDINGS CO., LTD. (KR) 2009-10-06 US disclosed
EP-1879873-A1 NEUROTHERAPEUTIC AZOLE COMPOUNDS SK Holdings Co., Ltd. (KR) 2008-01-23 EP disclosed
US-20060258718-A1 Neurotherapeutic azole compounds SK BIOPHARMACEUTICALS CO., LTD. (KR) 2006-11-16 US disclosed
WO-2006112685-A1 NEUROTHERAPEUTIC AZOLE COMPOUNDS SK HOLDINGS CO., LTD. (KR) 2006-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060258718-A1 Neurotherapeutic azole compounds CHRNA10, CHRNA4, CHRNA3 POLB 4187/4885ALDH1A1 1039/4885NR3C2 874/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.