Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | POLRMT | O00411 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18636645 | 0.82 | CA12 (0.41) | CA12CA1CA2CA9POLRMT | |
| SCHEMBL18636617 | 0.81 | CA12 (0.40) | CA12CA1CA2CA9POLRMT | |
| SCHEMBL7600077 | 0.81 | RNASEL (0.36) | POLRMT | |
| SCHEMBL22646509 | 0.79 | CA12 (0.39) | CA12CA1CA2CA9POLRMT | |
| SCHEMBL18666929 | 0.79 | CA12 (0.38) | CA12CA1CA2CA9POLRMT | |
| SCHEMBL16502855 | 0.78 | CA12 (0.39) | CA12CA1CA2CA9 | |
| SCHEMBL12253912 | 0.78 | CA12 (0.39) | CA12CA1CA2CA9 | |
| SCHEMBL3703700 | 0.78 | POLRMT (0.45) | POLRMT | |
| SCHEMBL26251486 | 0.77 | CA12 (0.37) | CA12CA1CA2CA9POLRMT | |
| SCHEMBL12253922 | 0.77 | CA12 (0.37) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009132135-A1 | 1' -SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2009-10-29 | — | — | WO | disclosed |