Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13668378 | 0.90 | LMNA (0.46) | KMT2AMEN1SMN1; SMN2LMNACYP3A4 | |
| SCHEMBL16575968 | 0.86 | LMNA (0.47) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16576002 | 0.86 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2LMNACYP3A4 | |
| SCHEMBL13668376 | 0.84 | KDM4E (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL14340653 | 0.81 | MEN1 (0.46) | KMT2AMEN1SMN1; SMN2LMNACYP3A4 | |
| SCHEMBL13668375 | 0.80 | RAB9A (0.46) | KMT2AMEN1SMN1; SMN2LMNACYP3A4 | |
| SCHEMBL13970853 | 0.75 | KDM4E (0.55) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13668372 | 0.75 | ALDH1A1 (0.42) | KMT2AMEN1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16575982 | 0.75 | NPC1 (0.42) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL14700374 | 0.74 | MAPK1 (0.64) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605191-B2 | polyoxyethylene glycol having end group of acrylamide derivatives, can be curing to provide medical device a surface coating which has hydrophilicity and high bioadaptability | TOYO GOSEI CO., LTD. (JP) | 2009-10-20 | — | — | US | disclosed |