Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13668496 | 0.92 | SMN1; SMN2 (0.46) | HTTSMN1; SMN2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13266193 | 0.89 | HTT (0.43) | HTTSMN1; SMN2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL10066691 | 0.86 | PTGS2 (0.39) | HTTSMN1; SMN2PTGS2MCL1PTGDR2 | |
| SCHEMBL10228504 | 0.85 | CNR2 (0.36) | HTTSMN1; SMN2ALDH1A1PTGS2NR1I2 | |
| SCHEMBL12927419 | 0.84 | SMN1; SMN2 (0.40) | HTTSMN1; SMN2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL14364642 | 0.84 | PTGS2 (0.40) | HTTSMN1; SMN2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13266251 | 0.80 | CNR2 (0.39) | HTTSMN1; SMN2ALDH1A1PTGS2MCL1 | |
| SCHEMBL13142187 | 0.79 | CASP1 (0.40) | HTTSMN1; SMN2PTGS2NR1I2MCL1 | |
| SCHEMBL822849 | 0.79 | HTT (0.61) | HTTSMN1; SMN2ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13668499 | 0.77 | HTT (0.50) | HTTSMN1; SMN2ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088883-B2 | Transition metal complex and process for producing conjugated aromatic compound using the transition metal complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-03 | — | — | US | disclosed |