Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2779580 | 0.88 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL2779581 | 0.88 | MEN1 (0.59) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL31442584 | 0.88 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL2383723 | 0.88 | NPC1 (0.56) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL24235206 | 0.86 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL13080506 | 0.86 | ALDH1A1 (0.69) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL1791859 | 0.85 | NPC1 (0.68) | NPC1RAB9AMEN1KMT2AMAPT | |
| Anisole SCHEMBL28145106 | 0.85 | MAPT (0.68) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL21823198 | 0.85 | MEN1 (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL19827139 | 0.85 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022010934-A2 | DEVICES AND METHODS FOR LIGHT-DIRECTED POLYMER SYNTHESIS | Twist Bioscience Corporation (US) | 2022-01-13 | — | — | WO | disclosed |
| US-7608582-B2 | Delivery vehicle comprising a modified MscL protein channel | APPLIED NANOSYSTEMS B.V. (NL) | 2009-10-27 | — | — | US | disclosed |
| US-7608582-B2 | Delivery vehicle comprising a modified MscL protein channel | APPLIED NANOSYSTEMS B.V. (NL) | 2009-10-27 | — | — | US | disclosed |
| US-7393828-B2 | Modified MscL protein channel | APPLIED NANOSYSTEMS B.V. (NL) | 2008-07-01 | — | — | US | disclosed |
| US-7393828-B2 | Modified MscL protein channel | APPLIED NANOSYSTEMS B.V. (NL) | 2008-07-01 | — | — | US | disclosed |
| US-20080138401-A1 | Delivery vehicle comprising a modified MscL protein channel | APPLIED NANOSYSTEMS B.V. (NL) | 2008-06-12 | — | — | US | disclosed |
| US-20080138401-A1 | Delivery vehicle comprising a modified MscL protein channel | APPLIED NANOSYSTEMS B.V. (NL) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138401-A1 | Delivery vehicle comprising a modified MscL protein channel | TRPM6, TRPM2, TRPM7 | NPC1 2375/4885RAB9A 2295/4885MEN1 600/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.