SCHEMBL2779581

SCHEMBL2779581

COc1cc(OC)cc(C(OC(=O)OC(C(=O)c2ccccc2)c2cc(OC)cc(OC)c2)C(=O)c2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
MAPT P10636 4/20 0.59
NPC1 O15118 4/20 0.59
RAB9A P51151 4/20 0.59
POLB P06746 2/20 0.59
ALDH1A1 P00352 6/20 0.54
CYP3A4 P08684 1/20 0.54
NPSR1 Q6W5P4 2/20 0.52
GAA P10253 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
HTT P42858 1/20 0.48
ADRB2 P07550 1/20 0.44
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PAX8 Q06710 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2779580 0.91 NPC1 (0.59) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL13080506 0.90 ALDH1A1 (0.69) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL22157293 0.89 MEN1 (0.52) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL22882581 0.89 MEN1 (0.52) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL21823198 0.88 MEN1 (0.57) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL291492 0.88 MEN1 (0.59) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL13669477 0.88 NPC1 (0.55) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL22761512 0.87 MEN1 (0.56) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL13019602 0.85 MEN1 (0.53) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL24235206 0.84 NPC1 (0.51) MEN1KMT2AMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1401851-B1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT BIOTECH GMBH (DE) 2008-07-02 EP claimed
US-7355036-B2 Two-stage protective groups for the synthesis of biopolymers FEBIT AG (DE) 2008-04-08 US claimed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 US claimed
EP-1981544-B1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE) HYDROGEL, PREPARATION METHOD THEREOF AND USE THEREOF KIST KOREA INSTITUTE OF SCIENCE AND TECH (KR) 2019-06-19 EP disclosed
US-9526699-B2 Biodegradable and thermosensitive poly(organophosphazene) hydrogel, preparation method thereof and use thereof KIST (KR) 2016-12-27 US disclosed
EP-2001513-B1 THERMOSENSITIVE POLYPHOSPHAZENE-BIOACTIVE MOLECULE CONJUGATES, PREPARATION METHOD THEROF AND USE THEREOF KOREA INST SCI & TECH (KR) 2016-06-01 EP disclosed
US-9017726-B2 Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-28 US disclosed
US-20140031289-A1 POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-01-30 US disclosed
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-01-03 US disclosed
EP-2540764-A2 Poly(organophosphazene) composition for biomaterials Korea Institute of Science and Technology (KR) 2013-01-02 EP disclosed
US-8313771-B2 Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-20 US disclosed
US-20090022683-A1 Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof KIST (KR) 2009-01-22 US disclosed
WO-2008153278-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-12-18 WO disclosed
WO-2008153277-A1 POLY(ORGANOPHOSPHAZENE) HYDROGELS FOR DRUG DELIVERY, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-12-18 WO disclosed
EP-2001513-A1 THERMOSENSITIVE POLYPHOSPHAZENE-BIOACTIVE MOLECULE CONJUGATES, PREPARATION METHOD THEROF AND USE THEREOF Korea Institute of Science and Technology (KR) 2008-12-17 EP disclosed
EP-1981544-A2 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE) HYDROGEL, PREPARATION METHOD THEREOF AND USE THEREOF KIST Korea Institute of Science and Technology (KR) 2008-10-22 EP disclosed
US-7355036-B2 Two-stage protective groups for the synthesis of biopolymers FEBIT AG (DE) 2008-04-08 US disclosed
WO-2007114549-A1 THERMOSENSITIVE POLYPHOSPHAZENE-BIOACTIVE MOLECULE CONJUGATES, PREPARATION METHOD THEROF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-10-11 WO disclosed
WO-2007083875-A2 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE) HYDROGEL, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2007-07-26 WO disclosed
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers MR. CHRISTOPHER SEAGON, ESQ. (DE) 2004-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS PHOSPHO1, PGLS, PHYKPL MEN1 1325/4885KMT2A 2496/4885MAPT 1436/4885
US-20040197851-A1 Two-stage protective groups for the synthesis of biopolymers CTRB2, OGG1, CPB2 MEN1 2823/4885KMT2A 2815/4885MAPT 3220/4885
US-20090022683-A1 Biodegradable and Thermosensitive Poly(Organophosphazene) Hydrogel, Preparation Method Thereof and Use Thereof PHOSPHO1, PGLS, LIPE MEN1 2005/4885KMT2A 4069/4885MAPT 3312/4885
US-20140031289-A1 POLY(ORGANOPHOSPHAZENE) CONTAINING DEGRADATION CONTROLLABLE IONIC GROUP, PREPARATION METHOD THEREOF AND USE THEREOF PHOSPHO1, PLCB3, INPP5D MEN1 1642/4885KMT2A 4325/4885MAPT 2670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.