Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036916 | 0.99 | CHRM1 (0.44) | NAAADGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL15315851 | 0.97 | HRH1 (0.44) | NAAADGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL10036917 | 0.94 | HRH1 (0.45) | DGKAGNAO1GNAI3GNAI1CHRM1 | |
| SCHEMBL420320 | 0.90 | CHRM1 (0.46) | DGKAGNAO1GNAI3GNAI1CHRM1 | |
| SCHEMBL13988121 | 0.89 | ACHE (0.43) | DGKAGNAO1GNAI3GNAI1CHRM1 | |
| SCHEMBL15781598 | 0.88 | GNAO1 (0.40) | NAAADGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL18906340 | 0.88 | GNAO1 (0.43) | NAAADGKAGNAO1GNAI3GNAI1 | |
| SCHEMBL19036161 | 0.87 | HRH1 (0.41) | GNAO1GNAI3GNAI1CHRM1CHRM2 | |
| SCHEMBL13160777 | 0.86 | HRH3 (0.44) | DGKAGNAO1GNAI3GNAI1CHRM1 | |
| SCHEMBL13160749 | 0.86 | CHRM1 (0.41) | DGKAGNAO1GNAI3GNAI1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258045-A1 | STRUCTURES INCLUDING ANTIMICROBIAL PEPTIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258045-A1 | STRUCTURES INCLUDING ANTIMICROBIAL PEPTIDES | NGLY1, VIP, PCBP1 | NAAA 325/4885DGKA 2096/4885GNAO1 4662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.