Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487379 | 0.82 | CASP6 (0.51) | VCAM1MAPTPOLBMAPK1ALDH1A1 | |
| SCHEMBL30305536 | 0.82 | VCAM1 (0.45) | VCAM1MAPTPOLBMAPK1ALDH1A1 | |
| SCHEMBL31090135 | 0.82 | CASP6 (0.51) | VCAM1MAPTPOLBMAPK1ALDH1A1 | |
| SCHEMBL2368685 | 0.82 | VCAM1 (0.45) | VCAM1MAPTPOLBMAPK1ALDH1A1 | |
| SCHEMBL805262 | 0.81 | PARP1 (0.49) | VCAM1MAPTPOLBMAPK1ALDH1A1 | |
| SCHEMBL1625709 | 0.81 | MAPT (0.44) | VCAM1MAPTPOLBMAPK1ALDH1A1 | |
| SCHEMBL70813 | 0.77 | MAPT (0.63) | VCAM1MAPTPOLBMAPK1ALDH1A1 | |
| SCHEMBL27579828 | 0.77 | MAPT (0.41) | VCAM1MAPTPOLBMAPK1ALDH1A1 | |
| SCHEMBL28350595 | 0.76 | MAPT (0.40) | VCAM1MAPTPOLBMAPK1ALDH1A1 | |
| SCHEMBL28623808 | 0.74 | MET (0.49) | VCAM1MAPTPOLBMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120660-A2 | SUBSTITUTED PYRIDOXAZINES | CARA THERAPEUTICS, INC. (US) | 2009-10-01 | — | — | WO | disclosed |