Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704685 | 0.85 | MAPT (0.61) | MAPTKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL29423180 | 0.85 | MAPT (0.61) | MAPTKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL5997173 | 0.85 | MAPT (0.61) | MAPTKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL22690991 | 0.85 | MAPT (0.61) | MAPTKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL13154843 | 0.81 | KDM4E (0.65) | MAPTKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL4703109 | 0.79 | KDM4E (0.56) | MAPTKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL4704433 | 0.78 | KDM4E (0.55) | MAPTKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL12562469 | 0.77 | MAPT (0.55) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL12602297 | 0.77 | RAB9A (0.66) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL4705921 | 0.74 | LMNA (0.44) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608643-B2 | Compounds for inhibiting KSP kinesin activity | SCHERING CORPORATION (US) | 2009-10-27 | — | — | US | disclosed |